Molecular mechanism(s) underlying neurodegeneration in SCA7 disease : Role of NOX enzymes and oxidative stress
Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide expansion in the SCA7 gene resulting in progressive ataxia and retinal dystrophy. SCA7 belongs to a group of neurodegenerative disorders called polyglutamine (polyQ) diseases, that...
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Format: | Doctoral Thesis |
Language: | English |
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Stockholms universitet, Institutionen för neurokemi
2015
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-119846 http://nbn-resolving.de/urn:isbn:978-91-7649-257-4 |