Proteolytic processing of the Alzheimer APP protein family during neuronal differentiation
Increased amyloid-β (Aβ) load in the brain, neurite degeneration, neuronal loss, and decreased levels of several neurotrophins are among the characteristics of Alzheimer’s disease (AD). Generation of Aβ occurs when the amyloid precursor protein (APP) is proteolytically processed by β- and γ-secretas...
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| Format: | Doctoral Thesis |
| Language: | English |
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Stockholms universitet, Institutionen för neurokemi
2009
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-31301 http://nbn-resolving.de/urn:isbn:978-91-7155-942-5 |