Internal duplications in alpha-helical membrane protein topologies are common but the nonduplicated forms are rare

Many alpha-helical membrane proteins contain internal symmetries, indicating that they might have evolved through a gene duplication and fusion event Here, we have characterized internal duplications among membrane proteins of known structure and in three complete genomes We found that the majority...

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Bibliographic Details
Main Authors: Hennerdal, Aron, Falk, Jenny, Lindahl, Erik, Elofsson, Arne
Format: Others
Language:English
Published: Stockholms universitet, Institutionen för biokemi och biofysik 2010
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-51243