STUDIES OF FACTORS AFFECTING INTRACELLULAR TOXICITY OF THE SCA7 DISEASE PROTEIN ATAXIN - 7 : FOCUS ON ATAXIN-7 DEGRADATION AND OXIDATIVE STRESS
Spinocerebellar ataxia type 7 (SCA7) is one of nine neurodegenerative disorders caused by expansion of CAG/polyglutamine repeats. Proteins carrying expanded polyglutamine (polyQ) domains are suggested to be resistant to degradation and aggregate. Furthermore, a negative correlation between aggregati...
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| Format: | Others |
| Language: | English |
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Stockholms universitet, Institutionen för neurokemi
2011
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-64167 http://nbn-resolving.de/urn:isbn:978-91-7447-410-7 |