Cell-penetrating peptides; chemical modification, mechanism of uptake and formulation development

Gene therapy holds the promise of revolutionizing the way we treat diseases. By using recombinant DNA and oligonucleotides (ONs), gene functions can be restored, altered or silenced according to the therapeutic need. However, gene therapy approaches require the delivery of large and charged nucleic...

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Bibliographic Details
Main Author: Ezzat, Kariem
Format: Doctoral Thesis
Language:English
Published: Stockholms universitet, Institutionen för neurokemi 2012
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-75537
http://nbn-resolving.de/urn:isbn:978-91-7447-464-0