Mechanistic Implications and Characterization of Anaplastic Lymphoma Kinase (ALK) mutations in Neuroblastoma
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that was first reported as a fusion partner of nucleophosmin in Anaplastic large cell lymphoma in 1994. ALK is involved in myriad of cancers including neuroblastoma which is the most common extracranial solid tumor affecting young childr...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Institutionen för molekylärbiologi (Medicinska fakulteten)
2015
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-106663 http://nbn-resolving.de/urn:isbn:978-91-7601-254-3 |