Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia

Timing and targeting of Type III secretion translocation of virulence effectors in Yersinia

The Type III secretion system (T3SS) is an important virulence mechanism that allows pathogenic bacteria to translocate virulence effectors directly into the cytoplasm of eukaryotic host cells to manipulate the host cells in favor of the pathogen. Enteropathogenic Yersinia pseudotuberculosis use a T...

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Bibliographic Details
Main Author: Ekestubbe, Sofie
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Institutionen för molekylärbiologi (Teknisk-naturvetenskaplig fakultet) 2017
Subjects:
Type III secretion system
virulence
translocation
Yersinia pseudotuberculosis
LcrV
YopN
effector targeting
phagocytosis inhibition
YopH
in vivo infection
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-130155
http://nbn-resolving.de/urn:isbn:978-91-7601-639-8

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-130155
http://nbn-resolving.de/urn:isbn:978-91-7601-639-8

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