Role of the CD47/SIRPα-interaction in regulation of macrophage phagocytosis
CD47 is a cell surface glycoprotein that is expressed by virtually all cells in the body. Binding of CD47 to the macrophage receptor Signal Regulatory Protein alpha (SIRPα) yields an inhibitory signal that counteracts phagocytosis. Red blood cells (RBCs) that lack CD47 are rapidly cleared from the c...
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| Format: | Doctoral Thesis |
| Language: | English |
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Umeå universitet, Integrativ medicinsk biologi
2008
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1574 http://nbn-resolving.de/urn:isbn:978-91-7264-526-4 |