Calmodulin mediated regulation of NF-kappaB in lymphocytes
NF-κB transcription factors are regulators of a wide spectrum of genes involved in immune responses and inflammation as well as cellular proliferation and survival. Transcriptionally competent NF-κB dimers are retained in the cytoplasm of resting cells by binding to inhibitors of NF-κB (IκBs). Stimu...
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Format: | Doctoral Thesis |
Language: | English |
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Umeå universitet, Molekylärbiologi (Medicinska fakulteten)
2008
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1895 http://nbn-resolving.de/urn:isbn:978-91-7264-659-9 |