The immortalization process of T cells : with focus on the regulation of telomere length and telomerase activity
Cellular immortalization is a major hallmark of cancer and is a multi-step process that requires numerous cell-type specific changes, including inactivation of control mechanisms and stabilization of telomere length. The telomeres at the chromosome ends are essential for genomic stability, and limit...
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| Format: | Doctoral Thesis |
| Language: | English |
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Umeå universitet, Patologi
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33466 http://nbn-resolving.de/urn:isbn:978-91-7459-007-4 |