Genetic and epidemiological studies of hereditary colorectal cancer

Lynch syndrome (Hereditary Nonpolyposis Colorectal Cancer, HNPCC) is the most common hereditary syndrome predisposing to colorectal cancer, accounting for 1-3% of all colorectal cancer. This multi-organ cancer predisposition syndrome is caused by mutations in the mismatch repair (MMR) genes, especia...

Full description

Bibliographic Details
Main Author: Cederquist, Kristina
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Medicinsk biovetenskap 2005
Subjects:
MSI
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-615
http://nbn-resolving.de/urn:isbn:91-7305-937-4