Ribonucleotide reductase and DNA damage

A prerequisite for a multicellular organism to survive is the ability to correctly replicate and repair DNA while minimizing the number of heritable mutations. To achieve this, cells need a balanced supply of deoxyribonucleoside triphosphates (dNTPs), the precursors for DNA synthesis. The rate-limit...

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Bibliographic Details
Main Author: Håkansson, Pelle
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Institutionen för medicinsk kemi och biofysik 2006
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-706
http://nbn-resolving.de/urn:isbn:91-7264-009-X