Peptidomimetics based on ring-fused 2-pyridones : probing pilicide function in uropathogenic E. coli and identification of Aβ-peptide aggregation inhibitors
This thesis describes the synthesis and biological evaluation of highly substituted, ring-fused 2-pyridones. The utility of the bicyclic 2-pyridones to gain fundamental insights into the disease processes of bacterial infections and Alzheimer’s disease has been investigated. The 2-pyridones have mai...
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| Format: | Doctoral Thesis |
| Language: | English |
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Umeå universitet, Kemiska institutionen
2006
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-909 http://nbn-resolving.de/urn:isbn:91-7264-157-6 |