Mechanisms of alloxan diabetogenicity

Suspensions of pancreatic islet cells from ob/ob-mice were incubated with Trypan Blue. Microscope photometry showed that apparently viable cells excluded the dye completely, whereas the nuclei of non-viable cells accumulated Trypan Blue by a saturable process. Alloxan rapidly increased the permeabil...

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Bibliographic Details
Main Author: Grankvist, Kjell
Format: Doctoral Thesis
Language:English
Published: Umeå universitet, Histologi med cellbiologi 1981
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-99341