Specific signaling through heteromeric PDGF receptor complexes
Platelet-derived growth factor (PDGF) is a potent mitogen and chemoattractant for mesenchymal cells and exert its effect by binding to two structurally related receptor tyrosine kinases, denoted α- and β-receptors. PDGF binding induces dimerization of its receptors, both homo-and heterodimerization,...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för cell- och molekylärbiologi
2000
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1067 http://nbn-resolving.de/urn:isbn:91-554-4785-6 |