Mass Spectrometric Analysis of Oxylipins : Application to Cytochrome P450-Dependent Metabolism
Cytochrome P450 (CYP) family 4 constitutes monoxygenases responsible for hydroxylation of fatty acids and other lipids. For example, CYP4F3 metabolizes leukotrienes and CYP4F8 prostaglandin H. Importantly, six of the twelve CYP4 enzymes are orphans, i.e., with an unknown biological function. The cat...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2009
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-109715 http://nbn-resolving.de/urn:isbn:978-91-554-7645-8 |