High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

High Content Analysis of Proteins and Protein Interactions by Proximity Ligation

Fundamental to all biological processes is the interplay between biomolecules such as proteins and nucleic acids. Studies of interactions should therefore be more informative than mere detection of expressed proteins. Preferably, such studies should be performed in material that is as biologically a...

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Bibliographic Details
Main Author: Leuchowius, Karl-Johan
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Molekylära verktyg 2010
Subjects:
in situ
proximity ligation
flow cytometry
high content screening
rolling circle amplification
in situ PLA
single-cell
single-molecule
protein interactions
drug screening
post-translational modifications
Molecular medicine
Molekylär medicin
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119530
http://nbn-resolving.de/urn:isbn:978-91-554-7739-4

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119530
http://nbn-resolving.de/urn:isbn:978-91-554-7739-4

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