Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates
Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrate...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för biokemi och organisk kemi
2010
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-119768 http://nbn-resolving.de/urn:isbn:978-91-554-7733-2 |