Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development

Heparan sulfate (HS) is a sulfated glycosaminoglycan expressed by all cells in the body. It is found at the cell surface and in the extracellular matrix where it binds a large amount of various ligands including growth factors and morphogens. HS is important for building up morphogen gradients durin...

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Bibliographic Details
Main Author: Dagälv, Anders
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2010
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-123474
http://nbn-resolving.de/urn:isbn:978-91-554-7825-4