Adrenal Bioactivation and Toxicity of 3-MeSO2-DDE, o,p´-DDD and DMBA Investigated in Tissue Slice Culture

Adrenal Bioactivation and Toxicity of 3-MeSO2-DDE, o,p´-DDD and DMBA Investigated in Tissue Slice Culture

I developed a precision-cut adrenal slice culture procedure to investigate cytochrome P450 (CYP) catalysed irreversible binding and adrenocorticolytic effects in human, rodent, and fish adrenal tissue, ex vivo. Autoradiography and radioluminography of exposed tissue slices showed that the potent adr...

Full description

Bibliographic Details
Main Author: Lindhe, Örjan
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för evolutionsbiologi 2001
Subjects:
Developmental biology
adrenal cortex
3-MeSO2-DDE
o
p´-DDD
DMBA
bioactivation
binding
toxic
Utvecklingsbiologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1538
http://nbn-resolving.de/urn:isbn:91-554-5185-3

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1538
http://nbn-resolving.de/urn:isbn:91-554-5185-3

Similar Items