Hit Identification and Hit Expansion in Antituberculosis Drug Discovery : Design and Synthesis of Glutamine Synthetase and 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Inhibitors
Since the discovery of Mycobacterium tuberculosis (Mtb) as the bacterial agent causing tuberculosis, the permanent eradication of this disease has proven challenging. Although a number of drugs exist for the treatment of tuberculosis, 1.7 million people still die every year from this infection. The...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Avdelningen för organisk farmaceutisk kemi
2011
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-155428 http://nbn-resolving.de/urn:isbn:978-91-554-8151-3 |