Mechanisms of Prodynorphin Gene Dysregulation in the Brain of Human Alcoholics
The endogenous opioid system (EOS) including dynorphin opioid peptides and κ-opioid receptor (KOR) plays a critical role in alcohol dependence. Aims of the thesis were to evaluate whether the EOS undergoes molecular adaptations in brain areas involved in cognitive control of addiction in human alcoh...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2011
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-158235 http://nbn-resolving.de/urn:isbn:978-91-554-8149-0 |