Wnt/β-catenin Signaling and Epigenetic Deregulation in Breast Cancer and Parathyroid Tumours

The Wnt/β-catenin signaling pathway is often deregulated in cancer. Here we investigate Wnt/β-catenin signaling, aberrant accumulation of β-catenin, and epigenetic deregulation in breast cancer and parathyroid tumours. An aberrantly spliced Wnt coreceptor LRP5 (LRP5Δ) is important for accumulation o...

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Bibliographic Details
Main Author: Svedlund, Jessica
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Endokrinkirurgi 2012
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173417
http://nbn-resolving.de/urn:isbn:978-91-554-8378-4