Conformationally Constrained Oligonucleotides for RNA Targeting
A short oligonucleotide sequence as in a single-stranded antisense oligo nucleotides (AON) or in double-stranded small interfering RNAs (siRNA) can modulate the gene expression by targeting against the cellular mRNA, which can be potentially exploited for therapeutic purposes in the treatment of dif...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Kemisk biologi
2012
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-179069 http://nbn-resolving.de/urn:isbn:978-91-554-8414-9 |