Cytochrome P450 Enzymes in the Metabolism of Vitamin D3
A cytochrome P450 enzyme in pig kidney that catalyzes the hydroxylations of vitamin D3 and C27-sterols was cloned. DNA sequence analysis of the cDNA revealed that the enzyme belongs to the CYP27 family. The recombinant kidney CYP27A enzyme catalyzed the 25-hydroxylation of vitamin D3 and the 27-oxy...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2002
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1791 http://nbn-resolving.de/urn:isbn:91-554-5242-6 |