In Vivo Active Drug Uptake and Efflux at the Blood-Brain Barrier : With Focus on Drug Transport Interactions
The blood-brain barrier (BBB) controls the movement of substances into and out of the brain. The tight junctions between endothelial cells and energy dependent transporters in the BBB influence rate and extent of drug distribution to the brain. The aim of this thesis was to study different methodolo...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2012
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180824 http://nbn-resolving.de/urn:isbn:978-91-554-8472-9 |