In Vivo Active Drug Uptake and Efflux at the Blood-Brain Barrier : With Focus on Drug Transport Interactions

The blood-brain barrier (BBB) controls the movement of substances into and out of the brain. The tight junctions between endothelial cells and energy dependent transporters in the BBB influence rate and extent of drug distribution to the brain. The aim of this thesis was to study different methodolo...

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Bibliographic Details
Main Author: Sadiq, Muhammad Waqas
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2012
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-180824
http://nbn-resolving.de/urn:isbn:978-91-554-8472-9