Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants

Dissecting the Genetic Basis of Systemic Lupus Erythematosus : The Pursuit of Functional Variants

Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease that primarily affects women during the childbearing years. SLE is characterized by the production of autoantibodies against nucleic acids and their interacting proteins. The exact molecular mechanisms leading to the bre...

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Bibliographic Details
Main Author: Delgado Vega, Angélica María
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Medicinsk genetik 2013
Subjects:
Systemic Lupus Erythematosus
SLE
Genetic Mapping
Association Studies
Functional Variants
TNFSF4
STAT4
IRF5
CD226
BLK
BANK1
Systemisk Lupus Erythematosus
Genetik
Genetisk Association
Funktionella Varianter
Lupus Eritematoso Sistémico
LES
Estudios de Asociación Genética
Variantes Funcionales
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196428
http://nbn-resolving.de/urn:isbn:978-91-554-8620-4

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196428
http://nbn-resolving.de/urn:isbn:978-91-554-8620-4

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