Importance of Hyaluronan-CD44 Signaling in Tumor Progression : Crosstalk with TGFβ and PDGF-BB Signaling
In order for solid tumors to metastasize, tumor cells must acquire the ability to invade the surrounding tissue and intravasate into blood- or lymph vessels, survive in the circulation and then extravasate at a distant site to form a new tumor. Overexpression of the glycosaminoglycan hyaluronan, and...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Science for Life Laboratory, SciLifeLab
2013
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198165 http://nbn-resolving.de/urn:isbn:978-91-554-8649-5 |