A generic capture assay for immunogenicity, using Biacore

The purpose of this investigation was to create and optimise a capture assay for the detectionof anti-drug antibodies (ADA) in human plasma, using Biacore. We also dealt with the nonspecificplasma binding to mouse-derived anti-biotin which may occur in the capture assay.By paying attention to these...

Full description

Bibliographic Details
Main Author: Engqvist, Martin
Format: Others
Language:English
Published: Uppsala universitet, Institutionen för biologisk grundutbildning 2013
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-198767