Mast Cell Progenitor Trafficking in Allergic Airway Inflammation
Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. The number of pulmonary mast cells is augmented in asthmatic patients and in mice with allergic a...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi
2013
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-206608 http://nbn-resolving.de/urn:isbn:978-91-554-8741-6 |