Mast Cell Progenitor Trafficking in Allergic Airway Inflammation

Mast cell progenitors originate from the bone marrow and migrate to the lungs via the blood. During maturation, these cells acquire granules that contain a potent array of bronchoconstrictive mediators. The number of pulmonary mast cells is augmented in asthmatic patients and in mice with allergic a...

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Bibliographic Details
Main Author: Dahlin, Joakim
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2013
Subjects:
IgE
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-206608
http://nbn-resolving.de/urn:isbn:978-91-554-8741-6