Novel Pentofuranose Chemistry to Modulate RNA Function
Chemical modifications of oligonucleotides provide an important tool to understand how the natural substrate works as well as how to improve their biochemical and biological properties as potential therapeutics and diagnostics. Our carba-LNA (2',4'-carba-bridged Locked Nucleic Acid) modifi...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Kemisk biologi
2014
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-233898 http://nbn-resolving.de/urn:isbn:978-91-554-9069-0 |