Evaluation of a UPLC-MS method using 18O-labelled water for the identification of hydrolytic degradants of drug substances
In this master’s thesis the hydrolytic degradation in 18O-water solutions of six drug substances has been studied. The aim was to develop a mass spectrometric method for easier identification of degradants, since hydrolysis in 18O-water will generate degradants with higher mass compared with hydroly...
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| Format: | Others |
| Language: | English |
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Uppsala universitet, Avdelningen för analytisk farmaceutisk kemi
2015
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-257712 |