The structural basis for the catalytic specificity of manganese lipoxygenases : 3D structure analysis of the lipoxygenase of Magnaporthe oryzae
Lipoxygenases (LOX) catalyze regio- and stereospecific oxygenation of polyunsaturated fatty acids to hydroperoxides. These hydroperoxides are further metabolized to leukotrienes and lipoxins in mammals, and are involved in asthma and inflammation. LOX of animals and plants contain iron as catalytic...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för farmaceutisk biovetenskap
2015
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-262762 http://nbn-resolving.de/urn:isbn:978-91-554-9347-9 |