Analysis of signaling pathway activity in single cells using the in situ Proximity Ligation Assay
A cell that senses signals from its environment uses proteins for signal transduction via post translational modifications (PTMs) and protein- protein interactions (PPIs) from cell membrane into the nucleus where genes controlling cell proliferation, differentiation and apoptosis can be turned on or...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Molekylära verktyg
2016
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-281716 http://nbn-resolving.de/urn:isbn:978-91-554-9529-9 |