Towards Understanding of Selectivity & Enantioconvergence of an Epoxide Hydrolase

Towards Understanding of Selectivity & Enantioconvergence of an Epoxide Hydrolase

Epoxide hydrolase I from Solanum tuberosum (StEH1) and isolated variants thereof has been studied for mapping structure-function relationships with the ultimate goal of being able to in silico predict modifications needed for a certain activity or selectivity. To solve this, directed evoultion using...

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Bibliographic Details
Main Author: Janfalk Carlsson, Åsa
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för kemi - BMC 2016
Subjects:
Epoxide hydrolase
Epoxide
Enantioselectivity
Regioselectivity
Enantioconvergence
Crystal structures
Biocatalysis
Immobilization
Transient kinetics
CASTing
Directed evolution
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-286557
http://nbn-resolving.de/urn:isbn:978-91-554-9586-2

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-286557
http://nbn-resolving.de/urn:isbn:978-91-554-9586-2

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