Methodological Studies on Covariate Model Building in Population Pharmacokinetic-Pharmacodynamic Analysis

Methodological Studies on Covariate Model Building in Population Pharmacokinetic-Pharmacodynamic Analysis

Population pharmacokinetic (PK) – pharmacodynamic (PD) modelling, using nonlinear mixed effects models, is increasingly being applied to obtain PK-PD information in drug development. Covariate modelling, the establishment of relationships between model parameters and patient characteristics, is unde...

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Bibliographic Details
Main Author: Wählby, Ulrika
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2002
Subjects:
Pharmaceutical biosciences
Farmaceutisk biovetenskap
Biopharmacy
Biofarmaci
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3050
http://nbn-resolving.de/urn:isbn:91-554-5469-0

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3050
http://nbn-resolving.de/urn:isbn:91-554-5469-0

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