Modelling and Simulation to Improve Antimalarial Therapy

Modelling and Simulation to Improve Antimalarial Therapy

The introduction of artemisinin-based combination therapy (ACT) substantially reduced malaria-related mortality and morbidity during the past decade. Despite the widespread use of ACT, there is still a considerable knowledge gap with regards to safety, efficacy and pharmacokinetic properties of thes...

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Bibliographic Details
Main Author: Lohy Das, Jesmin Permala
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2017
Subjects:
pharmacometrics
pharmacokinetics
pharmacodynamics
malaria
artemisinin
weekly dosing
resistant
pregnant populations
intermittent preventive therapy
parasite clearance
day 3 positivity
nomogram
Pharmaceutical Sciences
Farmaceutisk vetenskap
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330113
http://nbn-resolving.de/urn:isbn:978-91-513-0098-6

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-330113
http://nbn-resolving.de/urn:isbn:978-91-513-0098-6

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