The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing

The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing

ASF/SF2 is an essential splicing factor, required for constitutive splicing, and functioning as a regulator of alternative splicing. ASF/SF2 is modular in structure and contains two amino-terminal RNA binding domains (RBD1 and RBD2), and a carboxy-terminal RS domain. The results from my studies show...

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Bibliographic Details
Main Author: Dauksaite, Vita
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi 2003
Subjects:
Molecular biology
pre-mRNA splicing
alternative splicing
splicing regulation
SR proteins
ASF/SF2
modular domains
adenovirus
MLTU L1
E1A
MS2
Molekylärbiologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3579
http://nbn-resolving.de/urn:isbn:91-554-5737-1

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3579
http://nbn-resolving.de/urn:isbn:91-554-5737-1

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