The Regulation of Growth and Survival in Human Multiple Myeloma Cells by IGF-I Receptor Signaling
Multiple myeloma (MM) is an incurable B-cell malignancy mainly localized to the bone marrow. Our aim was to examine the growth- and survival-promoting role of the IGF-IR and its downstream signaling components in MM cells to identify potential targets for therapy. Octreotide, a somatostatin analog...
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| Format: | Doctoral Thesis |
| Language: | English |
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Uppsala universitet, Institutionen för genetik och patologi
2003
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| Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3586 http://nbn-resolving.de/urn:isbn:91-554-5740-1 |