Effects of acetylation and deacetylation inhibitors on DNA double strand breaks repair and cell survival

During treatment with ionizing radiation (IR), cells are killed mainly due to ionizing radiation caused acute damage to DNA, such as double-strand breaks, where opposite DNA strands in close proximity are cut. To counteract toxicity of double-strand breaks, cells have evolved DNA damage repair syste...

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Bibliographic Details
Main Author: Kalliontzi, Eugenia
Format: Others
Language:English
Published: Uppsala universitet, Institutionen för immunologi, genetik och patologi 2018
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-366545