Chitosan Polyplexes as Non-Viral Gene Delivery Systems : Structure-Property Relationships and In Vivo Efficiency
The subject of this thesis was to develop and optimize delivery systems for plasmid DNA (pDNA) based on biocompatible polymers, in particular chitosan, suitable for non-viral gene therapy. At the onset of this thesis, studies had reported conflicting results on the efficiency of chitosan-based gene...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för farmaci
2003
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3771 http://nbn-resolving.de/urn:isbn:91-554-5801-7 |