Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. For proper function, the FGFs...

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Bibliographic Details
Main Author: Lundin, Lars
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för genetik och patologi 2003
Subjects:
Pathology
FGF
FGFR
dimerisation
signal transduction
heparan sulfate
proteoglycan
heparin
VEGF
embryonal stem cell
endothelial cell
differentiation
Patologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3783
http://nbn-resolving.de/urn:isbn:91-554-5809-2

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3783
http://nbn-resolving.de/urn:isbn:91-554-5809-2

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