Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis
Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. The disease impairs ion and wate...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för medicinsk cellbiologi
2004
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3845 http://nbn-resolving.de/urn:isbn:91-554-5822-X |