Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis

Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. The disease impairs ion and wate...

Full description

Bibliographic Details
Main Author: Dragomir, Anca
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinsk cellbiologi 2004
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3845
http://nbn-resolving.de/urn:isbn:91-554-5822-X