Cyclic Sulfamide HIV-1 Protease Inhibitors : Design, Synthesis and Modelling

Cyclic Sulfamide HIV-1 Protease Inhibitors : Design, Synthesis and Modelling

Ten years ago, the first protease inhibitor targeting the human immunodeficiency virus (HIV) was approved for clinical use. Highly active antiretroviral therapy (HAART), which combined protease and reverse transcriptase inhibitors, quickly became the standard therapy for treating patients infected w...

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Bibliographic Details
Main Author: Ax, Anna
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för läkemedelskemi 2005
Subjects:
Pharmaceutical chemistry
AIDS
HIV
protease inhibitor
aspartic protease
molecular modelling
3D-QSAR
CoMFA
Farmaceutisk kemi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5803
http://nbn-resolving.de/urn:isbn:91-554-6253-7

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5803
http://nbn-resolving.de/urn:isbn:91-554-6253-7

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