Clinical Pharmacokinetics of the Antimalarial Artemisinin Based on Saliva Sampling

Artemisinin is the parent compound of a novel family of antimalarials. Repetitive administrations of artemisinin to both healthy volunteers and malaria patients have been shown to result in decreased plasma concentrations of the compound, most probably due to an autoinduction of different CYP450 enz...

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Bibliographic Details
Main Author: Gordi, Toufigh
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2001
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-608
http://nbn-resolving.de/urn:isbn:91-554-4956-5