Genotyping RNA and DNA using padlock probes

Genotyping RNA and DNA using padlock probes

Novel techniques are needed to investigate the genetic variation revealed in the first draft of the human genome sequence. Padlock probes are recently developed reagents, suitable for detecting single-nucleotide variations of DNA and RNA in situ or in solution. The probes are oligonucleotides of abo...

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Bibliographic Details
Main Author: Antson, Dan-Oscar
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för genetik och patologi 2001
Subjects:
Genetics
Padlock probe
enzymatic synthesis
PCR
in situ hybridization
RNA-templated DNA ligation
Genetik
Clinical genetics
Klinisk genetik
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-687
http://nbn-resolving.de/urn:isbn:91-554-5057-1

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-687
http://nbn-resolving.de/urn:isbn:91-554-5057-1

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