Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

Common mechanism for teratogenicity of antiepileptic drugs : Drug-induced embryonic arrhythmia and hypoxia-reoxygenation damage

The Antiepilptic drugs (AEDs) phenytoin (PHT), carbamazepine (CBZ), phenobarbital (PB), tri- and dimethadione (TMD and DMD) are known teratogens having a common malformation pattern in human and animal studies. This thesis was designed chiefly to test a hypothesis correlating the teratogenicity of t...

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Bibliographic Details
Main Author: Azarbayjani, Faranak
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för farmaceutisk biovetenskap 2001
Subjects:
Pharmaceutical biosciences
Atiepileptik drugs
embryonic heart
arrhythmia
cleft palate
ROS
antioxidants
Ikr
Farmaceutisk biovetenskap
Biopharmacy
Biofarmaci
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-692
http://nbn-resolving.de/urn:isbn:91-554-5065-2

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-692
http://nbn-resolving.de/urn:isbn:91-554-5065-2

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