Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics

The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological function...

Full description

Bibliographic Details
Main Author: Fransson, Åsa
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Ludwiginstitutet för cancerforskning 2008
Subjects:
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8514
http://nbn-resolving.de/urn:isbn:978-91-554-7122-4