Epigenetic Regulation of Gene Transcription in Hematopoietic Tumors
Epigenetic modifications were shown to play an essential role in tumorigenesis. Epigenetic mechanisms can alter transcription in several ways, through DNA methylation and/or through histone modification. DNA methylation at the TSS (transcriptional start site) has been implicated in tumor development...
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Format: | Doctoral Thesis |
Language: | English |
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Uppsala universitet, Institutionen för genetik och patologi
2008
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Online Access: | http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9206 http://nbn-resolving.de/urn:isbn:978-91-554-7257-3 |