Pancreatic Endocrine Tumourigenesis : Genes of potential importance

Pancreatic Endocrine Tumourigenesis : Genes of potential importance

Understanding signalling pathways that control pancreatic endocrine tumour (PET) development and proliferation may reveal novel targets for therapeutic intervention. The pathogenesis for sporadic and hereditary PETs, apart from mutations of the MEN1 and VHL tumour suppressor genes, is still elusive....

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Bibliographic Details
Main Author: Johansson, Térèse A.
Format: Doctoral Thesis
Language:English
Published: Uppsala universitet, Institutionen för medicinska vetenskaper 2008
Subjects:
Pancreatic endocrine tumour
Multiple endocrine neoplasia type 1
Tumourigenesis
Notch signalling
Notch1
Hes1
Neurog3
Neurod1
Men1
Ascl1
Pou3f4
Pdx1
Rpl10
Dlk1
Dkk1
Tph1
menin
Tumour biology
Tumörbiologi
Online Access:http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9294
http://nbn-resolving.de/urn:isbn:978-91-554-7290-0

Internet

http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9294
http://nbn-resolving.de/urn:isbn:978-91-554-7290-0

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